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Beilstein J. Org. Chem. 2021, 17, 2924–2931, doi:10.3762/bjoc.17.201
Graphical Abstract
Figure 1: a) Structures of hoshinoamides A and B. b) Structure of hoshinoamide C.
Scheme 1: Synthesis of resin-bound tripeptide 3 by SPPS. DIPEA: N,N-diisopropylethylamine; HCTU: O-(6-chloro-...
Scheme 2: Synthesis of dipeptide 6. HATU: 2-(7-azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorop...
Scheme 3: Synthesis of hoshinoamide A.
Beilstein J. Org. Chem. 2018, 14, 2348–2353, doi:10.3762/bjoc.14.210
Figure 1: Scope of the water-mediated synthesis of 4-acyl-NH-1,2,3-triazoles. General conditions: enaminone 1...
Scheme 1: The gram scale synthesis of 3a: (a) before reaction; (b) completed reaction; (c) the purified produ...
Scheme 2: The proposed reaction mechanism.